Meta-analysis on efficacy of Nosenazone sodium in treatment of patients with spinal muscular atrophy
Objective To verify the effectiveness of Nosenazone sodium in the treatment of patients with spinal muscular atrophy(SMA)by meta-analysis.Methods The study objects were the patients with SMA treated by Nosenazone sodium.The databases,such as VIP Database,China National Knowledge Infrastructure,Wanfang Database,PubMed,et.,were systematically searched from January 2016 to June 2023.RevMan5.7 was used to do the meta-analysis.The effectiveness of Nosenazone sodium for the domestic and foreign cases of SMA was systematically analyzed.Results A total of 232 patients with SMA were included in 11 literatures.The risk difference for improvement in SMA patients treated by Nosenazone sodium was 0.67(95%CI 0.39-0.96).Conclusion Nosenazone sodium for patients with SMA is obviously effective.