Effect of low-frequency pulse electrostimulation combined with rehabilitation robots on cognitive and motor functions in stroke patients
Objective To investigate the effect of low-frequency pulsed electrostimulation combined with rehabilitation robots for stroke patients.Methods Eighty stroke patients treated at Xi'an Encephalopathy Hospital of Traditional Chinese Medicine from January 2021 to August 2023 were selected for the randomized controlled trial.They were numbered upon admission;the first 40 patients were assigned to a control group,and the latter 40 to an observation group.The observation group included 25 males and 15 females who were(56.64±7.25)years old.The control group included 23 males and 17 females who were(56.34±6.34)years old.The control.group took basic treatment;in addition,the observation group took low-frequency pulsed electrostimulation and rehabilitation robot treatment.Both groups were treated 8 weeks.The clinical efficacies,cognitive function,motor function,and serum levels of brain-derived neurotrophic factor(BDNF),and nerve growth factor(NGF)were evaluated.t and x2 tests were applied.Results The effective rate in the observation group was higher than that in the control group[92.5％(37/40)vs.65.00％(26/40)],with a statistical difference(x2=9.04;P＜0.05).The score of National Institutes of Health Stroke Scale(NIHSS)in the observation group was lower than that in the control group[(6.34±2.18)vs.(8.29±2.57)],with a statistical difference(t=3.66;P＜0.05).After 4 and 8 weeks'treatment,the scores of cognitive function in the observation group were higher than those in the control group[(20.21±5.18)vs.(17.84±4.66)and(26.81±5.49)vs.(21.96±4.65)],with statistical differences(t=2.15 and 4.26;both P＜0.05);the scores of Fugl-Meyer Assessment and Barthel Index in the observation group were higher than those in the control group[(53.75±10.37)vs.(48.88±8.65),(63.69±13.54)vs.(55.00±12.25),(49.64±9.62)vs.(33.36±8.39),and(73.31±11.64)vs.(54.68±10.33)],with statistical differences(t=2.28,3.01,8.07,and 7.57;all P＜0.05);the levels of BDNF and NGF in the observation group were higher than those in the control group[(6.65±1.03)μg/L vs.(5.89±0.97)μg/L,(8.51±1.26)μg/L vs.(7.61±1.14)μg/L,(3.64±0.54)μg/L vs.(3.21±0.65)μg/L,(4.69±0.79)μg/L vs.(3.25±0.72)μg/L],with statistical differences(t=3.40,3.35,3.22,and 8.52;all P＜0.05).Conclusion Low-frequency pulsed electrostimulation combined with rehabilitation robots for stroke patients can improve their serum levels of BDNF and NGF and cognitive and motor functions.
万方数据
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