Gancao Xiexin oral care solution for improving oral state of stroke patients
Objective To explore the role of Gancao Xiexin oral care solution for improving the oral state of stroke patients.Methods Eighty stroke patients hospitalized at department of Neurosurgery,First Hospital,Henan University of Chinese Medicine from December 2021 to October 2023 were selected for the randomized controlled trial.They were divided into a control group and an observation group by the random number table method,with 40 cases in each group.There were 25 males and 15 females in the control group;they were(52.20±4.95)years old.There were 26 males and 14 females in the observation group;they were(52.20±6.37)years old.Thecontrol group used 0.9％sodium chloride injection(normal saline,NS)for oral care,the observation group used Gancao Xiexin oral care solution for oral care.The gingival index,plaque index,oral pH,oral moisture,oral odor,and oral mucositis before and after the treatment and adverse reactions were compared between the two groups.t and x2 tests were applied.Results Before the treatment,there were no significant differences in the gingival index,plaque index,oral pH,oral moisture,and oral odor between the two groups(all P＞0.05).After 5 and 10 days'treatment,the scores of gingival index,plaque index,oral moisture,and oral odor in the observation group were lower than those in the control group[(1.23±0.42)vs.(1.98±0.16),(0.65±0.48)vs.(1.10±0.30),(1.44±0.50)vs.(1.93±0.27),(0.78±0.48)vs.(1.20±0.52),(0.65±0.53)vs.(0.98±0.42),(0.15±0.36)vs.(0.65±0.53),(2.28±0.45)vs.(2.50±0.51),and(1.45±0.60)vs.(1.90±0.38)];the oral pH values in the observation group were higher than those in the control group[(6.53±0.08)vs.(6.42±0.11)and(6.98±0.10)vs.(6.62±0.14)];there were statistical differences(t=10.506,4.987,5.416,3.814,3.086,4.936,2.096,4.007,5.115,and 13.234;all P＜0.05).After the treatment,the incidence of oral mucositis in the observation group was lower than that in the control group[(5.0％(2/40)vs.15.0％(6/40)],with a statistical difference(x2=6.486;P＜0.05).No adverse reactions occurred in both groups.Conclusion Gancao Xiexin oral care solution can improve the oral health status of stroke patients and is easy and safe to operate,with high patient compliance,so it is worth being clinically generalized.
万方数据
维普
