composition ratio and drug resistance rate of pathogenic bacteria in pus of focal area of granulomatous lobular mastitis
Objective To investigate the composition ratio and drug resistance rate of pathogenic bacteria in the pus of the focal area of granulomatous lobular mastitis.Methods Two hundred patients with granulomatous lobular mastitis admitted to Tongchuan People's Hospital from August 2021 to August 2022 were selected as the study objects;they were(32.15±3.85)years old;their disease course was(29.56±6.12)days.The pus from the lesion area of all the patients was collected on the second day after admission for culture,isolation,and identification.The distribution of pathogenic bacteria in the pus was analyzed.Drug sensitivity tests were conducted on the Gram positive bacteria.The drug resistance of the pathogenic bacteria was analyzed.Results Among the 200 patients,Gram positive bacteria was detected in 162 ones(81.00％),Gram negative bacteria in 35(17.50％),and Candida albicans in 3(1.50％).Among the Gram positive bacteria,Corynebacterium accounted for 68.50％(137/200).Among the Gram negative bacteria,Acinetobacter accounted for 8.50％(17/200).Among the 137 cases of Corynebacterium pyogenes,Microbacterium,Aquatic Corynebacterium,Group G Corynebacterium,and Group A Corynebacterium accounted for 30.66％(42/137),15.33％(21/137),13.87％(19/137),and 9.49％(13/137),respectively.The resistance rates of genus Corynebacterium against oxacillin,clindamycin,and erythromycin were 74.74％(71/95),85.26％(81/95),and 81.05％(77/95),respectively;the resistance rates against vancomycin,linezolid,rifampicin,and gentamicin were 0.The resistance rates of Gram positive bacteria against oxacillin and clindamycin were 60.00％(15/25)and 72.00％(18/25),respectively;the resistance rates against vancomycin and linezolid were 0.Conclusions Gram-positive bacteria are the main pathogens in the pus of the focal area of granulomatous lobular mastitis,and Corynebacterium accounts for the highest proportion.Gram positive bacteria have a very low resistance rate to vancomycin,linezolid,rifampicin,and gentamicin,so the above drugs could be selected for the treatment.
万方数据
维普
