Impact of sleep state intervention nursing on immune function of patients undergoing cervical cancer excision
Objective To investigate the impact of sleep state intervention nursing on the immune function of patients undergoing cervical cancer excision.Methods Eighty-two patients with cervical cancer treated at Yulin Hospital,First Hospital,Xi'an Jiaotong University from October 2021 to October 2023 were selected for the randomized controlled trial.All the patients underwent hysterectomy and lymph node dissection.They were divided into a control group and an observation group by the random number table method,with 41 patients in each group.The control group received conventional nursing;in addition,the observation group received combined sleep state intervention.Both groups were intervened for one month.The postoperative recovery conditions of the two groups were compared.The Visual Analogue Scale(VAS)was use to evaluate the patients'pain in both groups 1 d,1 week,and 1 month after the operation.The patients'sleep quality was evaluated by the Pittsburgh Sleep Quality Index(PSQI)before and 1 month after the intervention.The serum levels of immunoglobulins were measured before and after the intervention.The patients'quality of life before and after the intervention was assessed in the physical,psychological,social,and environmental domains using the World Health Organization Quality of Life-BREF Scale(WHOQOL-BREF).t test and x2test were used for statistical comparison Results The postoperative time for off-bed activity,time to first flatus,time to first bowel movement,and hospital stay in the observation group were shorter than those in the control group[(11.62±1.45)h vs.(19.04±2.38)h,(29.88±4.01)h vs.(56.72±7.19)h,(2.90±0.47)d vs.(4.26±0.63)d,and(6.61±1.13)d vs.(10.84±2.45)d],with statistical differences(all P<0.001).The VAS scores of the observation group were lower than those of the control group 1 day,1 week and 1 month after surgery,and the differences were statistically significant(all P<0.001).One month after the intervention,the scores of PSQI and life quality and levels of immunoglobulins in the observation group were better than those in the control group,with statistical differences(all P<0.05).Conclusion Sleep state intervention can aid in the postoperative recovery of patients taking cervical cancer excision,and improve their sleep quality,immune function,and life quality.
Cervical cancerSleep state interventionSleep qualityImmune function