Observation on the effect of cardiac rehabilitation treatment in patients with heart disease after PCI
Objective To observe the effects of cardiac rehabilitation treatment on endothelin-1 level and cardiac function in patients with heart disease after percutaneous coronary intervention(PCI).Methods A total of 77 patients with heart disease after PCI admitted to Zhumadian Central Hospital from March 2022 to October 2023 were prospectively selected as the study objects and were divided into a control group(38 cases)and an observation group(39 cases)by the random number table method.In the control group,there were 22 males and 16 females,aged 43-69(57.71±5.28)years,and the course of disease was 1-7(3.76±1.25)years.In the observation group,there were 24 males and 15 females,aged 44-70(58.12±5.32)years,and the course of disease was 1-8(3.82±1.31)years.The control group received conventional treatment,and the observation group received cardiac rehabilitation therapy on the basis of the control group.Both groups were treated for 3 months.The mastery of cardiac rehabilitation(cardiac rehabilitation cognition survey scale),self-management ability[Coronary Heart Disease Self-Management Behavior Scale(CSMS)],exercise endurance(6 min walking distance),vascular endothelial function(endothelin-1,von Willebrand factor,and endothelium-dependent diastolic function),cardiac function(left ventricular ejection fraction,left ventricular end-systolic diameter,left ventricular end-diastolic diameter,and cardiac output),and quality of life(SF-36)were compared between the two groups before and after treatment.Independent sample t test,paired t test,and x2 test were used.Results After treatment,the mastery of cardiac rehabilitation[(60.72±2.96)points],self-management ability[(82.98±3.79)points],and exercise endurance[(496.88±27.34)m]of the observation group were better than those of the control group[(55.49±3.45)points,(78.39±4.22)points,and(451.69±35.45)m](all P＜0.05).After treatment,the levels of endothelin-1[(3.79±0.51)ng/L]and von Willebrand factor[(219.64±29.15)％]in the observation group were higher than those in the control group[(3.12±0.45)ng/L and(197.89±28.46)％],and the level of endothelium-dependent diastolic function[(5.15±0.43)％]was lower than that in the control group[(5.97±0.62)％](all P＜0.05).After treatment,the left ventricular ejection fraction[(64.96±1.26)％]and cardiac output[(6.13±0.45)min/L]in the observation group were higher than those in the control group[(61.99±1.31)％and(5.77±0.65)min/L],and the left ventricular end-systolic diameter[(37.79±1.37)mm]and left ventricular end-diastolic diameter[(41.65±1.28)mm]were shorter than those in the control group[(39.35±1.24)mm and(48.43±1.42)mm](all P＜0.05).After treatment,the scores of 8 dimensions of life quality of the observation group were higher than those of the control group(all P＜0.05).Conclusions Cardiac rehabilitation therapy has a definite effect on the treatment of heart disease patients after PCI,which can effectively improve the patients'vascular endothelial function and cardiac function,improve their quality of life,and facilitate their prognosis.It can be clinically applied and promoted.
Percutaneous coronary interventionHeart diseaseCardiac rehabilitation therapyEndothelin-1Cardiac function
万方数据
维普
