Effect of iRoot SP combined with single pointed root canal filling in treatment of patients with retrograde pulpitis
Objective To analyze the effect of iRoot SP combined with single pointed root canal filling in the treatment of patients with retrograde pulpitis.Methods A total of 120 patients with retrograde pulpitis who were treated in Department of Stomatology,Fujian Provincial Hospital from January 2022 to May 2023 were selected for the randomized controlled trial,and were divided into a control group and an observation group by the random number table method,with 60 cases in each group.There were 35 males and 25 females in the control group;they were(58.65±4.89)years old;their disease course was(4.12±1.36)years.There were 32 males and 28 females in the observation group;they were(59.34±5.27)years old;their disease course was(4.51±1.49)years.The control group received root canal filling using iRoot SP by the cold lateral pressure method.The observation group used iRoot SP and did single pointed root canal filling.The therapeutic effects,filling effects,periodontal indices[probing depth(PD),probing bleeding index(BOP),tooth mobility(TM),and clinical attachment level(CAL)],and levels of inflammatory factors[hypersensitive C-reactive protein(hs-CRP),tumor necrosis factor-α(TNF-α),and interleukin-1β(IL-1β)]in gingival crevicular fluid were compared between the two groups.t and x2 tests were applied.Results The total effective rate of the observation group was higher than that of the control group[96.67％(58/60)vs.86.67％(52/60)],with a statistical difference(x2=3.927;P＜0.05).The good filling rate of the observation group was higher than that of the control group[96.67％(58/60)vs.75.00％(45/60)],with a statistical difference(x2=11.582;P＜0.05).Before the treatment,there were no statistical differences in the PD,BOP,TM,CAL,and levels of hs-CRP,TNF-α,and IL-1 β between the two groups(all P＞0.05).After the treatment,the PD,BOP,TM,CAL,and levels of hs-CRP,TNF-α,and IL-1β in the observation group were lower than those in the control group[(1.97±0.23)mm vs.(2.76±0.26)mm,(0.84±0.19)vs.(1.31±0.23),(0.12±0.05)mm vs.(0.27±0.08)mm,(0.94±0.37)mm vs.(2.10±0.42)mm,(0.78±0.06)mg/L vs.(1.03±0.09)mg/L,(0.48±0.09)mg/L vs.(1.01±0.10)mg/L,and(56.68±2.34)ng/L vs.(63.16±2.57)ng/L],with statistical differences(t=17.628,12.203,12.316,16.053,17.903,30.515,and 14.441;all P＜0.05).Conclusion iRoot SP combined with single pointed root canal filling treatment for patients with retrograde pulpitis has good root canal sealing effect and can improve their periodontal status and inflammatory factor levels in gingival crevicular fluid of affected teeth,with significant overall therapeutic effect.
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