One case of primary pulmonary small cell ovarian carcinoma and literature review
This paper reports a case of primary pulmonary small cell carcinoma of the ovary and reviews the relevant literatures.Under the microscope,the cells are small or medium,and round,with sparse cytoplasm,deep nuclear staining,obscure nucleolus,and frequent mitotic images.Neuroendocrine markers,CgA,Syn,CD56,and INSM1,are positively expressed,while Vimentin and WT1 are negatively expressed;it is helpful for the diagnosis and differential diagnosis.The main treatment option is surgery with chemotherapy,but the prognosis is poor,with most patients dying within 2 years after diagnosis.