摘要
本文报道卵巢原发性肺型小细胞癌1例并复习总结相关文献.卵巢原发性肺型小细胞癌镜下呈不规则巢团状排列,细胞小或中等,呈圆形,胞质稀少,细胞核染色较深,核仁不明显,核分裂像多见.神经内分泌标志物CgA、Syn、CD56、INSM1表达阳性,Vimentin、WT1等表达阴性有助于诊断和鉴别诊断.治疗方案主要是手术治疗和辅助化疗,但预后欠佳,大多数患者在诊断后2年内死亡.
Abstract
This paper reports a case of primary pulmonary small cell carcinoma of the ovary and reviews the relevant literatures.Under the microscope,the cells are small or medium,and round,with sparse cytoplasm,deep nuclear staining,obscure nucleolus,and frequent mitotic images.Neuroendocrine markers,CgA,Syn,CD56,and INSM1,are positively expressed,while Vimentin and WT1 are negatively expressed;it is helpful for the diagnosis and differential diagnosis.The main treatment option is surgery with chemotherapy,but the prognosis is poor,with most patients dying within 2 years after diagnosis.
维普
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