Influencing factor analysis of class Ⅱ incision infection after radical operation for non-small cell lung cancer
Objective To investigate the influencing factors of class Ⅱ incision infection after radical operation for non-small cell lung cancer(NSCLC).Methods Sixty-two patients with class Ⅱ incision infection after radical operation for NSCLC in Ankang Hospital of Traditional Chinese Medicine from March 2018 to March 2022 were retrospectively selected as an infection group,and 85 patients who did not have incision infection were selected as a control group.The clinical data of all the patients were collected,and the influencing factors of class Ⅱ incision infection after radical operation for NSCLC were analyzed by logistic regression analysis.The secretions from the incision of infected patients were collected for pathogen detection.x2 test and independent sample t test were used for statistical analysis.Results In the infection group,there were 39 males and 23 females,aged(64.29±5.88)years.In the control group,there were 49 males and 36 females,aged(56.74±6.43)years.There was no statistically significant difference in the gender,intraoperative blood loss,smoking history,diabetes,or hypertension between the two groups(all P>0.05).The age in the infection group was older than that in the control group,the operation time was longer than that in the control group,and the proportions of thoracotomy,having visitors,and irrational use of antibiotics were higher than those in the control group(all P<0.05).Multivariate logistic regression analysis showed that age,operation time,operation method,whether there were visitors,and whether antibiotics were used rationally were the influencing factors of class Ⅱ incision infection after radical operation for NSCLC(all P<0.05).Sixty-two patients with class Ⅱ incision infection after radical operation for NSCLC were tested for pathogenic bacteria,and 96 strains were obtained.There were 54 strains of Gram-negative bacteria,accounting for 56.25%,among which Escherichia coli(27 strains,28.13%)was the main strain;there were 40 strains of Gram-positive bacteria,accounting for 41.67%,among which Staphylococcus aureus(19 strains,19.79%)was the main strain;there were 2 strains of fungi,accounting for 2.08%.Conclusions The pathogenic bacteria in patients with class Ⅱ incision infection after radical operation for NSCLC are mainly Gram-negative bacteria.Age,operation time,operation method,whether there are visitors,and whether antibiotics are used rationally are the influencing factors of class Ⅱ incision infection after radical operation for NSCLC.
Non-small cell lung cancerRadical operationIncision infectionDistribution of pathogenic bacteriaInfluencing factors