Clinical efficacy of matrix acupuncture combined with Jingulian capsules for post-stroke shoulder pain
Objective To evaluate the clinical efficacy of matrix acupuncture combined with Jingulian capsules in patients with post-stroke shoulder pain.Methods This study was a randomized controlled trial.Ninety-eight patients with post-stroke shoulder pain admitted to Ankang Hospital of Traditional Chinese Medicine from March 2022 to February 2024 were randomly divided into a control group and an observation group,with 49 patients in each group.In the control group,28 males and 21 females,aged(63.49±7.60)years,with a duration of disease of(3.32±1.19)months,received oral Jingulian capsules,2 capsules each time,3 times a day.In the observation group,26 males and 23 females,aged(64.60±8.37)years,with a duration of disease of(3.56±1.30)months,were treated with matrix acupuncture on the basis of the control group,30 min each time,3 times a week.Both groups were treated continuously for 8 weeks.The changes in Visual Analogue Scale(VAS),Fugl-Meyer Motor Function Assessment(FMA),Constant-Murley Shoulder Joint Scale(CMS),and ability of daily living(Barthel index)scores before and after treatment were compared between the two groups.Serum levels of endorphin,enkephalin,dynorphin,and inflammatory markers[interleukin 6(IL-6),tumor necrosis factor α(TNF-α),and nitric oxide(NO)]were detected,and the clinical efficacy was evaluated.t test and x2 test were used for statistical analysis.Results After 8 weeks of treatment,the VAS score of the observation group was lower than that of the control group[(3.67±1.23)points vs.(4.52±1.47)points],with a statistically significant difference(t=3.104,P=0.003);the FMA score,CMS score,and Barthel index of the observation group were higher than those of the control group[(26.43±5.89)points vs.(21.78±5.64)points,(30.22±6.83)points vs.(25.79±5.60)points,(60.65±7.15)points vs.(55.91±6.56)points],with statistically significant differences(t=3.991,3.511,and 3.419,all P＜0.001).Serum levels of endorphin,enkephalin,and dynorphin of the observation group were higher than those of the control group[(932.85±102.44)ng/L vs.(858.33±82.67)ng/L,(61.94±12.10)ng/L vs.(54.75±9.73)ng/L,(110.42±16.58)ng/L vs.(98.63±13.47)ng/L],with statistically significant differences(t=3.963,3.241,and 3.863,all P＜0.05);the levels of IL-6,TNF-α,and NO were lower than those of the control group[(47.22±8.54)pg/L vs.(54.68±9.10)pg/L,(16.41±4.12)ng/L vs.(19.88±5.47)ng/L,(19.48±4.12)μmol/L vs.(22.88±4.60)μmol/L],with statistically significant differences(t=4.184,3.547,and 3.854,all P＜0.001).The total effective rate of the observation group was higher than that of the control group[95.92％(47/49)vs.83.67％(41/49)],with a statistically significant difference(x2=4.009,P=0.045).Conclusion Matrix acupuncture combined with Jingulian capsules can significantly improve the degree of pain and dysfunction in patients with post-stroke shoulder pain,and has anti-inflammatory effects,which is worthy of clinical application.
万方数据
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