Influence of invasive ventilator treatment on dynamic blood gas,inflammation and other parameters in patients with severe pneumonia
Objective:To explore the influence of invasive ventilator treatment on dynamic blood gas,inflammation and other parameters in patients with severe pneumonia(SP).Methods:A total of 80 patients with SP admitted to Fuqing Hospital of Fujian from January 2018 to December 2022 were retrospectively analyzed.Patients were divided into two groups according to different respiratory support treatment plans,with 40 cases in each group.On the basis of conventional symptomatic treatment,the control group received routine treatment,while the observation group received invasive ventilator treatment.Blood gas analysis indicators,inflammation indicators and incidence of complications between two groups were compared.Results:There were no significant differences in C-reactive protein(CRP)and procalcitonin(PCT)levels,lactic acid,Δpartial pressure of carbon dioxide[ΔPaCO2(|PaCO2-40.0|)],partial pressure of arterial oxygen(PaO2)and oxygenation index between two groups before treatment(P＞0.05).After treatment,both inflammatory markers decreased in both groups(P＜0.001).The levels of CRP,PCT,lactic acid and ΔPaCO2 at day 7 after treatment in the observation group were lower than those in the control group,and the PaO2 and oxygenation index at day 3 and 7 after treatment were higher than those in the control group.The complication rate was lower(P＜0.05).Conclusions:Invasive ventilator treatment applied in patients with SP can dynamically improve blood gas analysis parameters,alleviate inflammatory reactions,reduce the incidence of complications,and improve prognosis.It is worthy of recommendation.
Severe pneumoniaInvasive ventilatorBlood gas analysisComplications
万方数据
维普
