To design slope measures for cross-sections of large-scale railway subgrade,this study introduced the concept of a slope measure combination,which connects diverse slope management strategies from the shoulder to the slope toe or top of the cutting,accompanied by the establishment of matching criteria.By aligning these combinations with conditions such as the subgrade type,subgrade height,and measure types on the left and right sides of each cross-section,the methodology retrieved from a database of slope measure combinations those that satisfy the given conditions,thereby completing the relevant design.This approach boasts advantages such as high design efficiency and broad applicability,having been successfully implemented in multiple railway projects,including Baotou-Yinchuan High-speed Railway,Shenyang-Baihe High-speed Railway,Weifang-Yantai High-speed Railway,and Ulanqab-Datong-Yuanping High-speed Railway,facilitating the digital and intelligent transformation of designing slope measures in cross sections of railway subgrade.Not confined to the railway sector,this method also offers valuable insights for upgrading slope design approaches in subgrades of municipal roads and highways.