甘肃中医药大学学报2024,Vol.41Issue(2) :81-85.DOI:10.16841/j.issn1003-8450.2024.02.13

铁棒锤炮制方法及"减毒存效"炮制原理研究进展

Research progress on processing method of Aconitum pendulum Busch and the processing principle of"reducing toxicity and retaining effectiveness"

曹瑞 牛江涛 金辉 陈红刚 李越峰
甘肃中医药大学学报2024,Vol.41Issue(2) :81-85.DOI:10.16841/j.issn1003-8450.2024.02.13

铁棒锤炮制方法及"减毒存效"炮制原理研究进展

Research progress on processing method of Aconitum pendulum Busch and the processing principle of"reducing toxicity and retaining effectiveness"

曹瑞 1牛江涛 2金辉 3陈红刚 3李越峰1
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作者信息

  • 1. 甘肃中医药大学药学院,甘肃 兰州 730101;甘肃省中药质量与标准研究重点实验室,甘肃 兰州 730000
  • 2. 青海大学医学部,青海 西宁 810000
  • 3. 甘肃中医药大学药学院,甘肃 兰州 730101
  • 折叠

摘要

通过查阅和整理近年来的相关文献,主要从铁棒锤的炮制方法、炮制对其化学成分及药理作用的影响及"减毒存效"的炮制原理等3个方面对铁棒锤的炮制研究进展进行概述.发现铁棒锤较常用、规范的炮制方法为水煮法、蒸制法及砂炒法,为规范铁棒锤的炮制工艺、阐明铁棒锤"减毒存效"的炮制原理、铁棒锤的深入研究开发及临床安全用药提供参考.

Abstract

By reviewing and sorting out the relevant literature in recent years,an overview of Aconitum pendu-lum Busch is provided from its processing methods,the influence of processing on its chemical composition and pharmacological action,and the processing principle of"reducing toxicity and retaining effectiveness".It was found that the commonly used and standardized processing methods of Aconitum pendulum Busch are boiling,steaming,and sand frying.This provides reference for standardizing the processing technology of Aconitum pendulum Busch,clarifying the processing principle of"reducing toxicity and retaining effectiveness"of Aconitum pendulum Bus-chrod,as well as its in-depth research and development,and clinical medication safety.

关键词

铁棒锤/炮制方法/化学成分/药理活性/减毒存效/综述

Key words

Aconitum pendulum Busch/processing method/chemical composition/pharmacological activity/re-ducing toxicity and retaining effectiveness/overview

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基金项目

甘肃省中药质量与标准研究重点实验室开放基金(zyzx-2020-23)

出版年

2024
甘肃中医药大学学报
甘肃中医学院

甘肃中医药大学学报

影响因子:0.563
ISSN:1003-8450
参考文献量35
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