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中药七情"相恶"配伍的历史变迁及现代研究进展

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查阅相关文献,从相恶内涵的沿革考证、相恶配伍临床应用、相恶药对的研究概况等3个方面对中药七情之"相恶"配伍进行概述.发现相恶内涵在历代本草中存在药效制约与毒性制约2种不同观点,目前普遍认为相恶是二药合用后,一种药物的某一种功效被另一种药物削弱.然而,相恶配伍在经方及现代临床中却有一定应用,且疗效显著.通过现代研究,发现相恶药对拮抗减效与药物炮制、配伍比例、组方中其他药物作用等有一定关联性.因此,相恶配伍是临床可用的一种特殊配伍关系,应辨证配伍,合理应用.
Historical changes and modern research progress of the mutual inhibition of compatibility among seven relations in Chinese medicine
This article summarizes the mutual inhibition of Chinese medicine compatibilityamong seven rela-tions in Chinese medicine by referencing relevant literature,focusing on historical research of its connotation,clini-cal applications,and the drug compatibility studies.It is noted that there are two different views on the mutual inhibi-tion of Chinese medicine compatibility in the history:efficacy restriction and toxicity restriction.While it is generally believed that the mutual inhibitionof Chinese medicine compatibility weakens the effect of one another after combi-nation of two drugs,it has shown remarkable effects in prescription and modern clinical practice.Modern research in-dicates that mutual inhibitionis correlated with drug processing,compatibility ratio,and other drugs in formulations.Therefore,he mutual inhibition is a special relationship that can be used clinically and should be applied rationally based on syndrome differentiation.

seven relations of traditional Chinese medicinemutual inhibitioncompatibilityhistorical changesmodern researchsummarize

张瑞欣、杨志军、杨秀娟、黄蓉、崔彦红、李一洁

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甘肃中医药大学药学院,甘肃 兰州 730101

甘肃省中药药理与毒理学重点实验室,甘肃 兰州 730000

中药七情 相恶 配伍 历史变迁 现代研究 综述

甘肃省中医药管理局科研基金资助项目甘肃省教育厅高等教育教学成果培育项目甘肃中医药大学"课程思政"示范课建设项目甘肃中医药大学"课程思政"示范课建设项目校级教学研究与教学改革课题校级教学研究与教学改革课题教育厅高等教育教学成果培育项目

GZK-2019-202020-1202020-32021-5YB-201705YBXM-022023-110

2024

甘肃中医药大学学报
甘肃中医学院

甘肃中医药大学学报

影响因子:0.563
ISSN:1003-8450
年,卷(期):2024.41(3)
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