Epidemiological and genetic characteristics of acute gastroenteritis outbreaks caused by sapovirus in one district of Beijing,2019-2023
Objective To analyse the epidemiological characteristics and genetic features of acute gastroenteritis outbreaks caused by sapovirus in a district of Beijing.Methods Epidemiological investigation date and fecal samples of the patients in acute gastroenteritis outbreaks in a district of Beijing from 2019 to 2023 were collected.Rotavirus,G Ⅰ and G Ⅱ norovirus,sapovirus,enteric adenovirus and astrovirus were identified by quantitative real-time PCR.Partial VP1 gene sequencing and phylogenetic analysis were performed for sapovirus positive samples.Results Sapovirus was detected in 29 outbreaks and the positive detection rate is 12.66％.There were two significant peaks in May to June and November.The outbreaks occurred mainly in kindergartens and primary schools.Five genotypes were detected,including G Ⅰ.6,G Ⅰ.1,G Ⅱ.3,G Ⅰ.2 and G Ⅰ.3.Conclusions G Ⅰ.6 was the predominant genotype of the outbreaks in a district of Beijing.Continuous surveillance should be carried out for further understanding of the molecular epidemiological characteristics of sapovirus.
NETL
NSTL
万方数据
