摘要
目的 了解艾滋病合并肺部感染疾病谱特征,为临床诊断提供思路.方法 收集2018年5月至2023年8月在北京地坛医院住院的152例艾滋病合并肺部感染者的临床数据,以患者出院诊断为最终诊断,采用SPSS 25.0进行统计学分析.结果 152例艾滋病合并肺部感染疾病谱构成依次为肺孢子菌肺炎(59.9％)、细菌性肺炎(55.9％)、巨细胞病毒肺炎(25.7％)、肺结核(23.7％)、真菌性肺炎(22.4％)、非结核分枝杆菌感染(6.6％).肺部单一病原体感染54例(35.5％),多重病原体感染98例(64.5％).多重病原体感染发生的比例在CD4+T淋巴细胞(简称CD4细胞)计数＜50个/μL、50～200个/μL、＞200个/μL的患者中分别为66.3％、25.5％、8.2％.结论 北京地坛医院艾滋病合并肺部感染住院患者主要感染肺孢子菌肺炎和细菌性肺炎,肺部感染类型常为混合感染,且多重病原体感染的发生与CD4细胞计数密切相关.
Abstract
Objective To investigate the characteristics of the spectrum of pulmonary infections in AIDS patients so as to provide ideas for clinical diagnosis.Methods The clinical data of 152 AIDS patients complicated with pulmonary infections were collected from the inpatient section of Beijing Ditan Hospital from May 2018 to August 2023,and SPSS 25.0 was used for statistical analysis.Results The spectrum of pulmonary infections among 152 AIDS patients were pneumocystis pneumonia(59.9％),bacterial pneumonia(55.9％),cytomegalovirus pneumonia(25.7％),pulmonary tuberculosis(23.7％),fungal pneumonia(22.4％),and nontuberculous mycobacterial infection(6.6％),successively.There were 54 cases(35.5％)of pulmonary infection by single pathogen and 98 cases(64.5％)by multiple pathogens.The proportions of multiple pathogen infection were 66.3％,25.5％,and 8.2％in patients with CD4 cell counts＜50 cells/μL,50-200 cells/μL,and＞200 cells/μL,respectively.Conclusions The AIDS inpatients complicated with pulmonary infections in Beijing Ditan Hospital were mainly pneumocystis pneumonia and bacterial pneumonia.The common type of pulmonary infection was mixed infection,and the occurrence of multiple pathogen infection was closely related to CD4 cell counts.
基金项目
北京市医院管理局登峰计划项目(DFL20191802)
北京市医院管理局临床医学发展专项资金项目(ZYLX202126)
NETL
NSTL
万方数据