Epidemiological characteristics and serum antibody screening among patients with tick-borne disease in a hospital
Objective To analyze the epidemiological characteristics of patients with tick-borne diseases in Mudanjiang Forestry Central Hospital,so as to provide baseline data for the prevention and control of the disease.Methods Serum samples were collected from the patients and tested for antibodies against tick-borne encephalitis,lyme disease and spotted fever rickettsiosis(spotted fever)by immunofluorescence assay and enzyme-link immunosorbent assay.The epidemiological and clinical data were collected to compare the differences in positive detection rates of gender,age,ethnic group,occupation,residence region and history of tick bite.Results From May to August,2023,a total of 525 serum samples of tick-born patients were tested.There were 341 cases were tested positive and the positive rate was 59.81%,including 91 cases of tick-borne encephaliti(17.33%),153 cases of lyme disease(29.14%),142 cases of spotted fever(27.05%)and 68 cases of mixed infections(12.95%).The antibody positive rate of 60.24%(300/498)among cases with a history of tick bites was higher than those without the history(51.85%,14/27),but no statistically significant difference was observed.The peak of patient visits in hospital was observed in May and June.The response rate of the patients in the hospital was higher than 94.51%.Conclusions Epidemics of ick-borne encephalitis,lyme disease and spotted fever rickettsiosis existed in Heilongjiang in 2023 and the surveillance as well as prevention and control of tick-borne disease should be enhanced.