完全型雄激素不敏感综合征合并无性细胞瘤一例
A Case Report of Complete Androgen Insensitivity Syndrome Complicated with Dysgerminoma
尹雨鑫 1王长河2
作者信息
- 1. 272013 山东省济宁市,济宁医学院临床医学院
- 2. 济宁市第一人民医院
- 折叠
摘要
雄激素不敏感综合征(androgen insensitivity syndrome,AIS)临床较为罕见,早期诊断困难.报告1例完全型雄激素不敏感综合征(complete androgen insensitivity syndrome,CAIS)合并无性细胞瘤患者的诊治经过,患者因腹胀2d,门诊行彩色超声提示盆腔肿物收入院,入院后先行盆腔肿物切除术治疗,因术前高雄激素血症原因不明,经染色体分析及基因检测最终明确诊断为CAIS合并无性细胞瘤,并最终行性腺恶性肿瘤根治术.目前该患者仍在密切随访中,病情稳定.通过回顾性分析该病例的临床特点及诊治经过,以期提高临床对于该病的认识.
Abstract
Androgen insensitivity syndrome(AIS)is rare and difficult to diagnose at an early stage.This paper reports the diagnosis and treatment of a patient with complete androgen insensitivity syndrome(CAIS)complicated with dysgerminoma.The patient was admitted to the hospital due to abdominal distension for 2 days and received color ultrasound in the outpatient department indicating pelvic tumor.After admission,pelvic tumor resection was performed.Since the cause of hyperandrogenemia was unknown before surgery,it was diagnosed as CAIS complicated with dysgerminoma by chromosome analysis and genetic testing,finally underwent radical resection of gonadal malignant tumor.At present,the patient is still under close follow-up and his condition is stable.Through retrospective analysis of the clinical characteristics and diagnosis and treatment of this case,in order to improve the clinical understanding of the disease.
关键词
雄激素迟钝综合征/性发育障碍/无性细胞瘤/雄激素增多症/病例报告Key words
Androgen-insensitivity syndrome/Disorders of sex development/Dysgerminoma/Hyperandrogenism/Case reports引用本文复制引用
出版年
2024
国家科技期刊平台
NSTL
万方数据