Pulmonary embolism is a serious complication during pregnancy.It presents suddenly with diverse clinical manifestations and is prone to misdiagnosis.Computed tomography angiography(CTA)is the definitive diagnostic tool.We report a case of pulmonary embolism diagnosed in a patient 40+days into an assisted reproductive pregnancy,who presented with palpitations,chest tightness,and shortness of breath.Cardiac color Doppler ultrasound estimated the pulmonary artery pressure at 63 mmHg(1 mmHg=0.133 kPa).The diagnosis was confirmed after chest CT and CTA.The patient improved after thrombolytic,anticoagulant,and symptomatic treatment,followed by an induced abortion to terminate the pregnancy.The prognosis is currently favorable.This case aims to heighten clinical awareness of early pregnancy pulmonary embolism.Besides taking a detailed medical history,clinicians must promptly perform relevant tests and examinations to achieve a rapid diagnosis and timely intervention.