Ovarian endometrioid carcinoma(OEC)has no special clinical manifestations in the early stage and is not easy to be detect.Trousseau syndrome is a thrombotic disease associated with malignancy.It is reported that one patient with OEC combined with Trousseau syndrome diagnosed and treated in our hospital has lower extremity venous thrombosis as the first symptom,and perioperative preparations are carried out at the same time as anticoagulation therapy,during which the patient still has pulmonary embolism,cerebral infarction,myocardial infarction and other multi-organ embolism.After a multidisciplinary evaluation,we performed surgical treatment and six courses of postoperative adjuvant chemotherapy,and there were no signs of recurrence and metastasis,and there was no new infarction,resulting in a good prognosis.Through this case,the understanding of the disease by clinical gynecologists is strengthened,and the disease is diagnosed and treated in a timely manner.Early use of antithrombotic drugs,active resection of the primary lesion,resumption of anticoagulation on the first day after surgery,close monitoring of coagulation function and timely adjustment of anticoagulant dosage can reduce the rate of disability and mortality due to embolism,improve the prognosis of patients,and protect women's health.