首页|18F-FDG PET/CT预测食管鳞癌新辅助放化疗疗效的研究进展

18F-FDG PET/CT预测食管鳞癌新辅助放化疗疗效的研究进展

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食管鳞癌(ESCC)的异质性较强.新辅助放化疗(nCRT)是局部晚期ESCC可手术者的首选治疗模式,但并非所有患者均能获益,在治疗前或治疗中准确鉴别出获益群体对于整体治疗策略的制定或及时调整具有重要意义.18F-FDG PET/CT功能显像包含丰富的肿瘤生物学信息,可在肿瘤组织形态学发生变化之前反映nCRT的疗效.笔者对18F-FDG PET/CT预测ESCC的nCRT疗效进展做一综述,以期从功能显像角度出发,筛选出局部晚期ESCC可手术者行nCRT后的获益人群.
Research progress of 18F-FDG PET/CT in evaluating the efficacy of neoadjuvant chemoradiotherapy for esophageal squamous cell carcinoma
Esophageal squamous cell carcinoma(ESCC)is highly heterogeneous.Neoadjuvant chemoradiotherapy(nCRT)is the preferred treatment mode for locally advanced operable patients,but not all them can benefit from this therapy modality.Accurate identification of benefit group before or during treatment is of great significance for the formulation or timely adjustment of overall treatment strategy.As a functional imaging,18F-FDG PET/CT contains rich tumor biological information,which can reflect the efficacy of nCRT before the change of tumor histomorphology.The authors provided a review of the progress in predicting the nCRT efficacy of ESCC using 18F-FDG PET/CT,with the aim of screening the beneficiaries of nCRT for locally advanced ESCC operable patients from a functional imaging perspective.

Esophageal squamous cell carcinomaFluorodeoxyglucose F18Positron-emission tomographyTomography,X-ray computedNeoadjuvant chemoradiotherapyResponse prediction

巩合义、伊艳、张健、李宝生

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山东第一医科大学附属中心医院肿瘤科,济南 250013

山东省肿瘤防治研究院,山东省放射肿瘤学重点实验室,山东第一医科大学附属肿瘤医院放疗科,济南 250117

食管鳞癌 氟脱氧葡萄糖F18 正电子发射断层显像术 体层摄影术,X线计算机 新辅助放化疗 疗效预测

2024

国际放射医学核医学杂志
中华医学会 中国医学科学院放射医学研究所

国际放射医学核医学杂志

CSTPCD
影响因子:0.227
ISSN:1673-4114
年,卷(期):2024.48(11)