国际放射医学核医学杂志2024,Vol.48Issue(11) :714-721.DOI:10.3760/cma.j.cn121381-202408035-00471

非小细胞肺癌脑转移放射治疗研究进展

Research progress in radiotherapy for brain metastases from non-small cell lung cancer

李排云 翟静 张同杰 张文学
国际放射医学核医学杂志2024,Vol.48Issue(11) :714-721.DOI:10.3760/cma.j.cn121381-202408035-00471

非小细胞肺癌脑转移放射治疗研究进展

Research progress in radiotherapy for brain metastases from non-small cell lung cancer

李排云 1翟静 1张同杰 2张文学1
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作者信息

  • 1. 天津医科大学总医院放射治疗科,天津 300052
  • 2. 佳木斯大学临床医学院,佳木斯 154007
  • 折叠

摘要

在世界范围内,肺癌的发病率与病死率排名均居于恶性肿瘤前列,其主要病理类型为非小细胞肺癌(NSCLC).脑部是肺癌最常见的远处转移部位之一,肺癌脑转移患者预后不良,其多学科治疗模式正在不断完善中.在靶向治疗与免疫治疗时代,放射治疗作为脑转移的常用局部治疗方法,其与靶向、免疫治疗的联合应用是目前临床研究的热点.笔者对NSCLC脑转移的放射治疗进展进行综述,以期为临床患者的综合治疗提供参考依据.

Abstract

In the world,the incidence and mortality rates of lung cancer are the highest of malignant tumors,with non-small cell lung cancer(NSCLC)representing the predominant pathological type.The brain is one of the most common distant metastatic sites of lung cancer,patients with brain metastases from lung cancer have a poor prognosis,and the modalities of multidisciplinary treatment are being improved.In the era of targeted therapy and immunotherapy,radiotherapy is a common local treatment modality for brain metastases and is widely used in clinical practice,the combined application of radiotherapy with targeted therapy or immunotherapy is a hot topic in clinical research at present.The authors reviewed the progress of radiotherapy for brain metastases from NSCLC,with the aim of providing a reference for the comprehensive treatment of patients in clinical practice.

关键词

非小细胞肺癌/肿瘤转移,脑/放射治疗/靶向治疗/免疫治疗

Key words

Non-small cell lung cancer/Tumor metastasis,brain/Radiotherapy/Targeted therapy/Immunotherapy

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出版年

2024
国际放射医学核医学杂志
中华医学会 中国医学科学院放射医学研究所

国际放射医学核医学杂志

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