Subarachnoid hemorrhage(SAH)is a cerebrovascular disease that is characterized by a high rate of disability and mortality.Astrocytes play a crucial role in brain injury and recovery following SAH.This paper summarizes the activation and polarization of astrocytes after SAH,their participation and mediation in early brain injury and delayed cerebral ischemia after SAH,and the extensive crosstalk between astrocytes and other brain cells,such as neurons,microglia,and vas-cular endothelial cells after SAH.In addition,the relevant targets and therapeutic methods for regu-lating astrocyte function after SAH are also listed here,offering some novel strategies for future translational therapies to alleviate the severe consequences of SAH.
万方数据
