Progress in animal models of hepatitis E virus infection
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戊型肝炎是由HEV引起的常见传染病,它的动物宿主比较广泛,在散发性病例发生过程发挥重要作用。研究HEV动物宿主、实验感染动物模型,对戊型肝炎的防控、HEV致病机制、跨物种传播、疫苗及治疗方案评估等相关研究具有现实意义。本文将对HEV常见动物宿主、实验感染动物模型进行综述。 Hepatitis E is a common infectious disease caused by HEV. HEV has a wide range of animal hosts playing an important role in occurrence of sporadic hepatitis E. The study of animal hosts and animal models of HEV infection has important practical significance for the prevention and control of hepatitis E, as well as for understanding the pathogenic mechanisms of HEV, cross species transmission, vaccine and treatment evaluation and other related research. This article reviews the common animal hosts of HEV and animal models of HEV infection.
Hepatitis E is a common infectious disease caused by HEV. HEV has a wide range of animal hosts playing an important role in occurrence of sporadic hepatitis E. The study of animal hosts and animal models of HEV infection has important practical significance for the prevention and control of hepatitis E, as well as for understanding the pathogenic mechanisms of HEV, cross species transmission, vaccine and treatment evaluation and other related research. This article reviews the common animal hosts of HEV and animal models of HEV infection.
Hepatitis E virusAnimal hostExperimental infectionAnimal model