Objective To understand the implementation status of prevention of mother-to-child transmission of HBV in Naqu City,so as to identify problems in the prevention work,and reduce the incidence of mother-to-child transmission.Methods A survey was conducted in 6 hospitals randomly selected from the eastern,central and western regions of Naqu City from January 1 to December 31,2020.The rate of HBV screening for pregnant women before delivery,the HBsAg positive rate,the timely vaccination rate of the 1st dose of hepatitis B vaccine(HepB1)combined with hepatitis B immunoglobulin(HBIG)for newborns of HBsAg positive mothers,the reasons for delayed vaccination,the status of post-vaccination serological test(PVST)were investigated.Results A total of 4132 pregnant women were investigated in 6 hospitals,and the screening rate of HBV markers for pregnant women before delivery was 100.00％(4 132/4 132),among whom the HBsAg positive rate was 10.36％(428/4 132).Of the 428 newborns delivered by HBsAg positive mothers,93.46％(400/428)were timely vaccinated with HepB1 combined with HBIG,while 28 were delayed,mainly due to low birth weight(premature birth)(19 cases)and neonatal jaundice(6 cases).There were 100 infants who met the conditions for PVST,but only 21.00％(21/100)were tested,and all HBsAg results were negative.However,7 infants were anti-HBs negative,and only 2 of them were given a supplemental dose of HepB vaccine.The main reason for not performing PVST in 79 infants was that their parents did not know about it,accounting for 82.28％(65/79).Conclusions The HBsAg screening rate of hospitalized pregnant women in Naqu City reaches 100％.Low birth weight and neonatal jaundice are the main reasons for delayed vaccination of HepB1 combined with HBIG.Lack of awareness among parents is the main reason for not performing PVST.
Hepatitis BHBsAgPrevention of mother-to-child transmissionInvestigation
NETL
NSTL
万方数据
