The efficacy analysis of argon-helium cryoablation for localized prostate cancer
Objective To investigate the efficacy and safety of argon-helium cryoablation for localized prostate cancer.Methods The data of 21 patients with localized prostate cancer who under-went argon-helium cryoablation in our hospital from January 2014 to December 2019 were retrospective-ly analyze.Serum total prostate specific antigen(tPSA),international prostate symptom score(IP-SS),quality of life(QOL),MRI and whole body scan were evaluated,and biochemical recurrence and complications were recorded.Results At 3 months after surgery,the serum tPSA,IPSS and QOL scores of all patients were significantly lower than those before treatment,with statistical significance(all P＜0.001).The serum tPSA level 6 months after surgery was lower than that 3 months after sur-gery,and the difference was statistically significant[(0.012±0.013)ng/mL vs.(0.096±0.174)ng/mL,P＜0.05].Reexamination of prostate MRI one year after surgery indicated that prostate vol-ume decreased significantly,from pre-operation(44.85±19.66)mL to post-operation(19.90± 11.63)mL,with statistical significance(P＜0.05).During follow-up,there were no deaths,no lo-cal progression or metastasis,two patients had long-term complications after surgery,and 1 patient had biochemical recurrence.Conclusions Cryoablation with argon-helium knife is an effective treatment for localized prostate cancer,and it can relieve urinary tract symptoms and improve quality of life.It is an optional treatment for localized prostate cancer.
NETL
NSTL
万方数据
维普
