Analysis of the effect of dynamic carbon dioxide pneumoperitoneal pressure management in pa-tients with renal cancer surgery
Objective To investigate the effect of dynamic carbon dioxide pneumoperitoneum pressure management in patients with renal cancer surgery.Methods A total of 106 patients with re-nal cancer who underwent elective retroperitoneal laparoscopic partial nephrectomy who were admitted to our hospital from January 2020 to January 2022 were selected and randomly divided into two groups,with 53 cases in each group.In the control group,the carbon dioxide pneumoperitoneum pressure was maintained at 12 mmHg,while the experimental group was based on the concept of enhanced recovery surgery,and the carbon dioxide pneumoperitoneum pressure was dynamically adjusted according to the operation process.The changes of blood pressure,heart rate,partial pressure of carbon dioxide(PaCO2),airway pressure,partial pressure of end-tidal carbon dioxide(PET),renal function and quality of life before and after operation were compared between the two groups before and after renal artery occlusion,and perioperative indexes and complication rate of the two groups were recorded.Re-sults There were no significant differences in blood pressure,heart rate,airway pressure,PaCO2 and PET between the two groups at different time periods(all P>0.05).The intraoperative blood loss,postoperative drainage volume and time of renal artery occlusion in experimental groups were shorter than those in control group,and the incidence of postoperative bleeding in experimental groups was lower than that in control group,with statistical significance(all P<0.05).The serum creatinine(Scr),urea nitrogen(BUN)of experimental groups on the 3rd day after surgery were lower than those of control group,and the differences were statistically significant(all P<0.05).The life quality of experimental group was higher than that of control group 6 months after operation,and the difference was statistically significant(P<0.05).Conclusions Dynamic carbon dioxide pneumoperitoneum pressure management can effectively reduce the intraoperative blood loss,reduce the time of renal ar-tery occlusion,reduce postoperative drainage,protect renal function,and improve the quality of life in patients with renal cancer undergoing posterior laparoscopic partial nephrectomy.Circulatory and re-spiratory systems were not significantly affected.