The influencing factors of urinary tract infection after kidney stone surgery and the predictive value of serum RBP4 and Cys C detection
Objective To analyze the influencing factors of urinary tract infection after kidney stone surgery and the predictive value of serum retinol-binding protein 4(RBP4),Cystatin C(Cys C)detection.Methods From February 2020 to September 2022,clinical data of 160 patients with kidney stones in our hospital were retrospectively analyzed,and were divided into two groups according to the occurrence of postoperative urinary tract infection(80 cases)and no urinary tract infection(80 ca-ses).General data of the two groups were statistically analyzed,the distribution of pathogens in pa-tients with urinary tract infection was analyzed,and the comparison and correlation of serum RBP4 and Cys C levels between the two groups were statistically analyzed,and the influencing factors of postoper-ative urinary tract infection were analyzed by univariate and multifactor Cox regression.Results The proportion of patients with urinary tract infection who did not use antibiotics before operation was higher than that without urinary tract infection(P＜0.05),the proportion of ureteral stents retained before operation was higher than that in the group without urinary tract infection,the proportion of operation duration≥1 h and ureteral catheter retention duration≥1 week after operation were higher than those in no urinary tract infection group(all P＜0.05).The serum levels of RBP4 and Cys C in the group with urinary tract infection were higher than those in the group without urinary tract infection(all P＜0.05).Serum RBP4 and Cys C levels were positively correlated(r=0.800,P＜0.05).Univariate a-nalysis showed that the risk factors of postoperative urinary tract infection included no preoperative anti-biotic application,preoperative ureteral stent retention,operation time ≥ 1 h,postoperative ureteral catheter retention time ≥ 1 week,RBP4,Cys C(all P＜0.05).Multivariate Cox regression analysis showed that the risk factors of postoperative urinary tract infection included preoperative ureteral stent indwelling,preoperative antibiotic not applied,operation time ≥ 1 h,postoperative ureteral catheter in-dwelling time ≥ 1 week,RBP4,Cys C(all P＜0.05).Conclusions The influencing factors of urina-ry tract infection after renal stone operation included preoperative ureteral stent retention,no antibiotic application before surgery,operation time≥1 h,postoperative ureteral catheter retention time ≥ 1 week,RBP4,Cys C,serum RBP4,Cys C detection had high predictive value for urinary tract infec-tion.
Kidney CalculiUrinary Tract InfectionRetinol Binding Protein 4Cystatin C
NETL
NSTL
万方数据
