Value of enhanced multi-slice spiral CT in differential diagnosis of different subtypes of renal carcinoma
Objective To study the value of multi-slice spiral CT enhanced scanning in differ-ential diagnosis of different subtypes of renal carcinoma.Methods From June 2018 to June 2023,100 patients with renal carcinoma admitted to hospital were retrospectively selected.All patients were con-firmed by surgical pathological examination,including 23 chromophobe cell carcinoma,31 papillary cell carcinoma and 46 clear cell carcinoma.All patients received enhanced renal CT scan before opera-tion,and the CT imaging characteristics were observed and analyzed.The renal cancer subtypes were determined by CT classification criteria.The consistency between postoperative pathological classification results and CT classification results was compared,and the CT values of patients with different sub-types were measured and compared at different scanning periods.Results The accuracy of CT in the diagnosis of chromophobe cell carcinoma was 91.30%(21/23),papillary cell carcinoma was 74.19%(23/31),clear cell carcinoma was 93.48%(43/46),and the overall diagnosis accuracy was 87.00%(87/100).There was a high consistency between CT diagnosis and pathologic diagnosis(Kappa=0.804).There were no significant differences in renal pelvis compression,clear boundary,diameter,contour protrusion and lobe segmentation among different subtypes of renal carcinoma(all P>0.05).Compared with the patients with chromophobe and papillary cell carcinoma,the number of heterogeneous enhancement,necrotic cyst change and false envelope signs in clear cell carcinoma pa-tients was higher,and the difference was significant(all P<0.05).Compared with chromophobe and clear cell carcinoma,the number of tumor calcification cases in papillary cell carcinoma patients was higher,and the difference was significant(all P<0.05).Compared with the patients with chromo-phobe cell carcinoma and clear cell carcinoma,the CT value of papillary cell carcinoma in plain scan period was higher,and the difference was significant(all P<0.05).Compared with chromophobe cell carcinoma and papillary cell carcinoma,the CT values of renal pelvis,medullary and cortical stages in clear cell carcinoma patients were higher,and the difference was significant(all P<0.05).Conclu-sions The CT signs of patients with chromophobe cell carcinoma,papillary and clear cell carcinoma are different.Enhanced multi-slice spiral CT is of great value in the differential diagnosis of different subtypes of renal carcinoma.