The effect of holmium laser enucleation of the prostate on urodynamics and serum T-PSA and F-PSA levels in patients with benign prostatic hyperplasia
Objective To observe the therapeutic effect of holmium laser enucleation of the prostate(HoLEP)on patients with benign prostatic hyperplasia(BPH)and its impact on urodynamics and serum levels of total prostate-specific antigen(T-PSA)and free prostate-specific antigen(F-PSA).Methods A total of 128 BPH patients admitted to our hospital from January 2021 to June 2023 were selected as the study objects,and the patients were divided into observation group(HoLEP treatment,64 cases)and control group(PKEP treatment,64 cases)by random number table method.The surgical indexes,urinary flow dynamics indexes,serum T-PSA,F-PSA levels and sexual function before and after treatment were compared between the two groups,and postoperative complications were followed up.Results The intraoperative blood loss in the observation group was less than that in the control group,and the duration of bladder irrigation,urinary catheter indentation and hospitalization were shorter than those in the control group(all P＜0.05).After treatment,the maximum urinary flow,maximum bladder capacity and residual urine volume of the two groups were better than before treatment,and the urinary flow dynamics indexes of the observation group were better than the control group after treatment(all P＜0.05).The T-PSA and F-PSA levels of the two groups after treatment were lower than those before treatment,and the T-PSA and F-PSA levels of the observation group after treatment were lower than those of the control group(all P＜0.05).IIEF-5 and CIPE scores after treatment were higher than those before treatment,and IIEF-5 and CIPE scores in observation group were higher than those in control group after treatment(all P＜0.05).The incidence of postoperative complications in the observation group was lower than that in the control group(P＜0.05).Conclu-sions HoLEP surgery for BPH has less trauma and faster recovery compared to PKEP surgery,which is beneficial for improving the patient's urodynamic indicators and serum T-PSA and F-PSA levels.It has less impact on the patient's sexual function and fewer complications.
Prostatic HyperplasiaTransurethral Resection of ProstateUrodynamicsFree Prostate Specific AntigenTotal Prostate Specific Antigen
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