Analysis of clinical characteristics and risk factors of urinary tract infection in pregnant women with gestational diabetes mellitus
Objective To investigate the clinical characteristics and related risk factors of uri-nary tract infection in pregnant women with gestational diabetes mellitus(GDM).Methods A total of 289 pregnant women diagnosed with GDM admitted to our hospital from January 2017 to December 2021 were selected for retrospective analysis of the incidence,pathogen distribution and drug resistance of urinary tract infections in pregnant women with GDM.Logistic regression model was used to analyze the risk factors associated with urinary tract infections in pregnant women with GDM.Results Among 289 pregnant women with gestational diabetes mellitus,32 cases had urinary tract infection,the inci-dence rate was 11.07％.A total of 32 strains of pathogenic bacteria were detected,of which Esche-richia coli[53.13％(17/32)]was the main pathogen,followed by Streptococcus agalactiae[15.63％(5/32)].Escherichia coli has a high resistance rate to Ampicillin,and a low resistance rate to antibacterial drugs such as Amikacin,β-lactamase inhibitor mixtures,and Carbapenems.Uni-variate analysis showed that triglyceride(TG),high-density lipoprotein cholesterol(HDL-C),glyco-sylated hemoglobin(HbA1c)were risk factors for urinary tract infection in pregnant women with GDM(P＜0.05).Multivariate logistic regression analysis showed that TG were independent risk factors for urinary tract infection in pregnant women with GDM(OR=1.276,95％CI:1.066-1.526,P＜0.05).Conclusions TG is associated with the occurrence of urinary tract infection in pregnant women with GDM.Appropriate measures should be taken to reduce the incidence of urinary tract infection and to rationally choose antimicrobial drugs according to the patient's condition.
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