序列相似家族19成员A5(family with sequence similarity 19, member A5，FAM19A5)是近年来新发现的脂肪因子。研究发现，FAM19A5与肥胖、胰岛素抵抗、非酒精性脂肪肝病等代谢性疾病密切相关，这表明FAM19A5有希望成为新型代谢性疾病生物标记物。本文对FAM19A5与代谢性疾病的相关性及可能的作用机制进行归纳综述，以期为FAM19A5的相关研究提供线索。 Family with sequence similarity 19, member A5 (FAM19A5) is a newly discovered adipokine in recent years. It has been found that FAM19A5 is closely associated with metabolic diseases such as obesity, insulin resistance, and non-alcoholic fatty liver disease, which suggests that FAM19A5 is promising as a novel metabolic disease biomarker. In this paper, we summarize and review the correlation between FAM19A5 and metabolic diseases and the possible mechanisms of action, in order to provide clues for the related research of FAM19A5.
Research progress of novel adipokine FAM19A5 in metabolic diseases
Family with sequence similarity 19, member A5 (FAM19A5) is a newly discovered adipokine in recent years. It has been found that FAM19A5 is closely associated with metabolic diseases such as obesity, insulin resistance, and non-alcoholic fatty liver disease, which suggests that FAM19A5 is promising as a novel metabolic disease biomarker. In this paper, we summarize and review the correlation between FAM19A5 and metabolic diseases and the possible mechanisms of action, in order to provide clues for the related research of FAM19A5.
Family with Sequence Similarity 19, Member A5adipokineMetabolic diseases
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