国际内分泌代谢杂志2024,Vol.44Issue(1) :47-50.DOI:10.3760/cma.j.cn121383-20230722-07028

妊娠诱发库欣综合征的诊疗进展

Clinical advances in pregnancy-induced Cushing′s syndrome

吴晗 徐丹 王君 吴炎
国际内分泌代谢杂志2024,Vol.44Issue(1) :47-50.DOI:10.3760/cma.j.cn121383-20230722-07028

妊娠诱发库欣综合征的诊疗进展

Clinical advances in pregnancy-induced Cushing′s syndrome

吴晗 1徐丹 1王君 1吴炎1
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作者信息

  • 1. 深圳市人民医院(暨南大学第二临床医学院,南方科技大学第一附属医院)内分泌科,深圳 518020
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摘要

妊娠诱发库欣综合征是指妊娠状态所诱发的库欣综合征,一般患者在分娩后或终止妊娠后症状得到缓解。该病非常罕见,但对母体与胎儿均产生严重危害。妊娠诱发库欣综合征和妊娠合并库欣综合征在临床表现上相似,但在发病机制及治疗方法上存在差异,诊断较为困难,治疗面临挑战。本文主要针对妊娠诱发库欣综合征的发病机制、诊断和治疗进行简要综述,旨在为妊娠诱发库欣综合征患者的临床管理提供借鉴。 Pregnancy-induced Cushing′s syndrome refers to Cushing′s syndrome induced by the state of pregnancy. Generally, patients experience relief in symptoms after delivery or termination of pregnancy. This disease is very rare, but it can cause serious harm to both the mothers and the fetuses. The clinical manifestations of pregnancy-induced Cushing′s syndrome and pregnancy with Cushing′s syndrome are similar, but there are differences in pathogenesis and treatment methods, making diagnosis difficult and treatment challenging. This article mainly reviews the pathogenesis, diagnosis, and therapies of pregnancy-induced Cushing′s syndrome, aiming to provide possible suggestions for the clinical management of this condition.

Abstract

Pregnancy-induced Cushing′s syndrome refers to Cushing′s syndrome induced by the state of pregnancy. Generally, patients experience relief in symptoms after delivery or termination of pregnancy. This disease is very rare, but it can cause serious harm to both the mothers and the fetuses. The clinical manifestations of pregnancy-induced Cushing′s syndrome and pregnancy with Cushing′s syndrome are similar, but there are differences in pathogenesis and treatment methods, making diagnosis difficult and treatment challenging. This article mainly reviews the pathogenesis, diagnosis, and therapies of pregnancy-induced Cushing′s syndrome, aiming to provide possible suggestions for the clinical management of this condition.

关键词

库欣综合征/妊娠/肾上腺增生/促黄体生成素/绒毛膜促性腺激素受体

Key words

Cushing′s syndrome/Pregnancy/Adrenal hyperplasia/LHCGR

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基金项目

国家自然科学基金青年基金(82000768)

深圳市科技计划基础研究面上项目(JCYJ20220530152813030)

National Natural Science Foundation of China(Youth Fund)(82000768)

出版年

2024
国际内分泌代谢杂志
中华医学会,天津医科大学

国际内分泌代谢杂志

CSTPCD
影响因子:0.842
ISSN:1673-4157
参考文献量28
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