Research advances in pheochromocytoma combined with paraganglioma
Pheochromocytoma(PCC)and paraganglioma(PGL)are rare neuroendocrine tumors,that can occur separately or simultaneously.However,the PCC combined with PGL is even rarer.Since the PCC combined with PGL has the clinical characteristics of both PCC and PGL,together with the complex conditions,and it can be nonsynchronous,it is easy to be misdiagnosed.Therefore,improving the under-standing of PCC combined with PGL is of great significance for the diagnosis,treatment,and follow-up of PPGL patients.This article will review the progress in the epidemiology,genetics,clinical manifestations,diagnostic methods,treatment,and prognosis of PCC combined with PGL,in order to improve the clinicians'understanding of this disease.
PheochromocytomaParagangliomaPheochromocytoma combined with paraganglioma