抗甲状腺球蛋白抗体与分化型甲状腺癌关系研究现状
Research status of the relationship between anti-thyroglobulin antibodies and differentiated thyroid cancer
刘梦月 1孙楠 1罗全勇 1邱忠领1
作者信息
- 1. 上海交通大学医学院附属第六人民医院核医学科,上海 200233
- 折叠
摘要
甲状腺癌作为目前发病率上升最快、甲状腺外科最常见的内分泌恶性肿瘤而备受关注,手术切除联合131I核素治疗、促甲状腺激素抑制治疗是其主要治疗方法.分化型甲状腺癌是甲状腺癌中最常见的类型.甲状腺球蛋白是分化型甲状腺癌术后随访最常用的肿瘤标志物.然而,甲状腺球蛋白抗体(thyroglobulin antibodies,TgAb)的存在会影响甲状腺球蛋白的检测,因此,在甲状腺癌患者的随访过程中,TgAb的检测显得尤为重要.本综述将探讨TgAb的检测在分化型甲状腺癌患者的诊断和随访中的临床应用,为临床实践提供有益的参考.
Abstract
Thyroid cancer has attracted much attention as the fastest rising incidence and the most common endocrine malignant tumor in thyroid surgery.At present,treatment methods primarily include sur-gical resection+131I radionuclide therapy+thyroid stimulating hormone suppression therapy.Differentiated thyroid cancer is the most common type of thyroid cancer.Thyroglobulin is the most commonly used tumor marker in postoperative follow-up of differentiated thyroid cancer.However,thyroglobulin antibodies(TgAb)can affect the detection of thyroglobulin.Therefore,the detection of TgAb is particularly important in the follow-up of patients with thyroid cancer.This review will focus on the clinical application of TgAb de-tection in the diagnosis and follow-up of patients with differentiated thyroid cancer,and provide a useful ref-erence for clinical practice.
关键词
分化型甲状腺癌/甲状腺球蛋白/抗甲状腺球蛋白抗体/诊断/随访Key words
Differentiated thyroid cancer/Thyroglobulin/Thyroglobulin antibody/Diagnosis/Fol-low-up引用本文复制引用
出版年
2024
NETL
NSTL
万方数据