Research progress on the treatment of obstructive sleep apnea syndrome with GLP-1RA
Obstructive sleep apnea syndrome(OSAS)is a common chronic sleep disorder character-ized by episodic narrowing of the upper airway during sleep leading to partial or complete airway closure.0-besity is one of the main factors in its occurrence and deterioration,and patients often have systemic inflam-mation,insulin resistance,type 2 diabetes and cardiovascular disease,etc.However,there is no clinical drug for treating OSAS.Glucagon-like peptide-1 receptor agonists(GLP-1RA)not only perform well in weight loss,but also improve many comorbidities of OSAS.Therefore,this paper reviews the effects of GLP-1RA on OSAS.