首页|2022美国替妥木单抗治疗甲状腺眼病的专家共识:解读与思考

2022美国替妥木单抗治疗甲状腺眼病的专家共识:解读与思考

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甲状腺眼病(TED)是一种以眼球后及眶周组织浸润性病变为特征的一种自身免疫性疾病,严重影响患者的生活质量和身心健康,并增加个人、家庭和社会的经济负担.替妥木单抗(teprotumumab)因其独特的功效,成为唯一获美国食品药品监督管理局批准治疗TED的靶向生物制剂.2022年9月,由国际著名TED及眼整形专家Douglas教授牵头制定了第一部替妥木单抗治疗TED的专家共识,主要从药物适用范围、使用前患者评估、治疗方案、安全性、有效性以及随访监测等方面进行了阐述,为临床医师治疗TED提供了具体的指导与借鉴.
Interpretation and comments of 2022 American Expert Consensus on the Use of Teprotumumab for the Management of Thyroid Eye Disease
Thyroid eye disease(TED)is an autoimmune disease characterized by infiltrative lesions of the retroocular and periorbital tissues,which can seriously affect the quality of life,physical and mental health,and increase the economic burden of families and society.Teprotumumab became the first drug ap-proved by the Food and Drug Administration(FDA)to for the treatment of TED in 2020.In September 2022,Professor Douglas,an internationally renowned expert in TED and oculoplastic medicine,led the team and wrote the first expert consensus on the treatment of TED with teprotumumab.This consensus describes not only the indications and contraindications of teprotumumab therapy,but also patient evaluation,treat-ment plan,safety,follow-up monitoring,etc.,providing practical guidance and reference for clinicians.

TeprotumumabThyroid eye diseaseTreatmentsExpert consensus

黄文彬、何志伟、刘洲君、徐书杭、刘超

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南京中医药大学附属中西医结合医院,江苏省中医药研究院内分泌科,国家中医药管理局瘿病证治重点研究室,南京 210028

苏州市吴中人民医院,苏州 215128

替妥木单抗 甲状腺眼病 治疗 专家共识

江苏省研究生实践创新计划项目

SJCX23_0819

2024

国际内分泌代谢杂志
中华医学会,天津医科大学

国际内分泌代谢杂志

CSTPCD
影响因子:0.842
ISSN:1673-4157
年,卷(期):2024.44(4)
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