Abstract
The skin constitutes the primary barrier between the human body and the external environment.The skin microbiome plays an important role in the microecosystem,on the skin surface and mediates multiple facets of the skin barrier function,including physical,chemical,microbial,and immune barriers.In this review,we discuss the host-microbiota interactions in barrier maintenance and disruption,implications for skin disorders such as atopic dermatitis,psoriasis,and rosacea,and the latest strategies for targeting the skin microbiota to improve the skin barrier.
基金项目
Nanjing Incubation Program for National Clinical Research Center(2019060001)
Key Project of Social Development in Jiangsu Province(BE2020632)
国家自然科学基金(82073446)
国家自然科学基金(82103735)
Chinese Academy of Medical Sciences(CAMS)Innovation Fund for Medical Sciences(2021-I2M-1-059)
国家重点研发计划(2022YFC3601800)
NETL
NSTL
万方数据