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Skin Microbiota and the Skin Barrier

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The skin constitutes the primary barrier between the human body and the external environment.The skin microbiome plays an important role in the microecosystem,on the skin surface and mediates multiple facets of the skin barrier function,including physical,chemical,microbial,and immune barriers.In this review,we discuss the host-microbiota interactions in barrier maintenance and disruption,implications for skin disorders such as atopic dermatitis,psoriasis,and rosacea,and the latest strategies for targeting the skin microbiota to improve the skin barrier.

skin barriermicrobiotaimmuneatopic dermatitisStaphylococcus aureus

Ming-Yang Wu、Xu Yao

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Department of Allergy and Rheumatology,Jiangsu Key Laboratory of Molecular Biology for Skin Diseases and STIs,Hospital for Skin Diseases(Institute of Dermatology),Chinese Academy of Medical Sciences and Peking Union Medical College,Nanjing,Jiangsu 210042,China

Jiangsu Key Laboratory of Molecular Biology for Skin Diseases and STIs,Nanjing,Jiangsu 210042,China

Nanjing Incubation Program for National Clinical Research CenterKey Project of Social Development in Jiangsu Province国家自然科学基金国家自然科学基金Chinese Academy of Medical Sciences(CAMS)Innovation Fund for Medical Sciences国家重点研发计划

2019060001BE202063282073446821037352021-I2M-1-0592022YFC3601800

2024

国际皮肤性病学杂志
中华医学会,中国医学科学院皮肤病研究所

国际皮肤性病学杂志

CSTPCD
影响因子:0.276
ISSN:1673-4173
年,卷(期):2024.7(1)
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