Abstract
Introduction:Eruptive pseudoangiomatosis(EP)is a rare type of cutaneous exanthema characterized by red angioma-like papules.An association of EP with viral infection has been reported.We herein describe 4 pediatric patients who showed a new variant of EP-associated rash with atypical clinical features and positivity for parvovirus B19 infection.Case presentation:Pediatric patients showed a new variant of EP-associated rash with atypical clinical features by dermoscopy and reflectance confocal microscopy.The papules were localized to the face(cheeks,forehead,and eyelids).Dermoscopy showed multiple red dots suggesting dilated capillaries surrounded by reddish structureless areas;and in vivo reflectance confocal microscopy(RCM)showed perivascular inflammation around the dermal papillae.However,characteristic perilesional halo was absent.In all patients,serology revealed evidence of active infection by parvovirus B19.Discussion:Few cases of a facial pseudoangiomatous rash that is related to parvovirus B19 infection and lacks the typical anemic halo have been reported in the literature.Conclusion:These cases provide new information on the clinical spectrum of EP and its association with parvovirus.
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