Burkitt lymphoma presenting with ascites as the initial symptom:A case report and literature review
The clinical and pathological data of a case of Burkitt lymphoma with ascites as the primary clinical manifestation were reported.In addition,relevant literature was reviewed.The patient,a 29-year-old male,was admitted with abdominal distension and fatigue for 20 days.Physical examination demonstrated abdominal distension with positive shifting dullness.Imaging examination showed extensive peritoneal thickening and large amounts of ascites,with increased metabolism of 18F-fluorodeoxyglucose(18F-FDG)in the peritoneum.Abdominal paracentesis revealed cloudy,orange-colored ascites,positive Rivalta test,98.9%monocytes,and lactate dehydrogenase(LDH)of 1 214 U/L.Ctrospin preparations of ascites were stained with hematoxylin-eosin staining(HE),and immunohistochemistry and fluorescence in situ hybridization confirmed the diagnosis of Burkitt lymphoma.After chemotherapy with the R-Hyper CVAD regimen(rituximab-hyperfractionated cyclophosphamide,vincristine,adriamycin and dexamethasone),the patient achieved complete clinical remission.After 25 months of follow-up,the patient remains in good health,with no recurrence or metastasis.The diagnosis of Burkitt lymphoma is highly dependent on pathology examination,characterized by rapid onset,aggressive progression,and high malignancy.Molecular testing is essential for diagnosis and differential diagnosis.Timely and accurate diagnosis and treatment are critical for patient prognosis.
万方数据
维普
