首页|早期圆锥角膜诊断技术的研究进展

早期圆锥角膜诊断技术的研究进展

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圆锥角膜是导致全球致盲性角膜疾病的重要原因,早期因缺乏典型症状而难以诊断,未能及时干预治疗以至病情严重需要角膜移植才来就诊.而中国角膜库稀缺,给患者复明带来严重困难.目前,随着角膜地形图、角膜生物力学、眼前节光学相干断层扫描(optical coherence tomography,OCT)和角膜共聚焦显微镜(corneal confocal microscopy,CCM)等眼科设备及人工智能(artificial intelligence,AI)技术的进步,大大提高了早期圆锥角膜的诊断效率.各种眼科诊断设备可以从角膜的形态学、生物力学、角膜厚度、活体细胞结构等方面提供多种角膜参数,而AI技术可以综合多种参数,辅助高效诊断早期圆锥角膜,在临床上有较高的实用价值.早期圆锥角膜的诊断技术为及时干预治疗圆锥角膜、帮助挽救患者视力提供了参考依据.
Advances in diagnostic techniques for early keratoconus
Keratoconus is a leading cause of corneal blindness worldwide.Early diagnosis is challenging due to the lack of typical symptoms,often resulting in delayed treatment and severe disease progression necessitating corneal transplantation.The scarcity of corneal donors in China further complicates patient outcomes.Recent advancements in ophthalmic devices,such as corneal topography,corneal biomechanics,optical coherence tomography(OCT)of the anterior segment,and corneal confocal microscopy(CCM),along with artificial intelligence(AI)technologies,have significantly improved the efficiency of early keratoconus diagnosis.These diagnostic tools provide comprehensive corneal parameters including morphology,biomechanics,corneal thickness,and cell structures.AI can integrate these parameters to assist in the efficient diagnosis of early keratoconus,demonstrating high clinical utility.Early diagnostic techniques for keratoconus offer crucial insights for timely intervention and treatment,aiding in the preservation of patient vision.

keratoconuscorneal ectasiaartificial intelligence

徐未清、陈琦

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广西壮族自治区人民医院眼科,广西眼健康重点实验室,广西壮族自治区卫生健康委员会眼部与相关全身疾病人工智能筛查技术重点实验室,广西医学科学院眼科疾病医学研究所,南宁 530021

右江民族医学院临床学院,广西百色 533000

圆锥角膜 角膜扩张 人工智能

广西眼科疾病临床医学研究中心项目

桂科AD19245193

2024

临床与病理杂志
中南大学

临床与病理杂志

CSTPCD
影响因子:0.559
ISSN:1673-2588
年,卷(期):2024.44(5)