Changes in the pathogen spectrum of pediatric community-acquired lobar pneumonia in Jingmen area before and after the outbreak of COVID-19
Objective:Pediatric community-acquired lobar pneumonia is a common respiratory disease in pediatrics,with high consumption of medical resources and frequent complications.Targeted treatment based on its pathogen spectrum is crucial.This study aims to investigate the changes in the pathogen spectrum of pediatric community-acquired lobar pneumonia 3 years before and 3 years after the outbreak of coronavirus disease 2019(COVID-19),with the goal of providing guiding clinical medication.Methods:Clinical data were collected from 820 pediatric patients with community-acquired lobar pneumonia hospitalized at Jingmen Central Hospital from January 1,2017,to January 8,2023.The cases were divided into a pre-pandemic group and a post-pandemic group,and the differences in pathogen spectrum between the 2 groups were compared.Results:Significant differences were observed between the 2 groups in terms of age of onset,month of onset,pathogen positivity rate,and distribution of the pathogen spectrum(all P<0.05).The proportion of school-aged children decreased significantly,and the fluctuations in the month of onset were smaller post-pandemic compared to pre-pandemic.In terms of pathogen distribution,the top 3 in the pre-pandemic group were mixed infections,single mycoplasma infections,and single bacterial infections,while in the post-pandemic group,they were mixed infections,single bacterial infections,and single mycoplasma infections.Streptococcus was the most common bacterial infection in both groups.Respiratory syncytial virus was the most common viral infection pre-pandemic,while influenza B virus was the most common post-pandemic.Conclusion:After the COVID-19 outbreak,the pathogen spectrum of pediatric community-acquired lobar pneumonia in the Jingmen area has changed,with a significant increase in the proportion of bacterial and influenza B virus infections.
万方数据
维普
