首页|间歇性θ短阵脉冲刺激小脑蚓部对脑卒中患者下肢运动功能障碍的影响

间歇性θ短阵脉冲刺激小脑蚓部对脑卒中患者下肢运动功能障碍的影响

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目的:探讨间歇性θ短阵脉冲刺激(intermittent theta-burst stimulation,iTBS)小脑蚓部对脑卒中患者下肢运动功能障碍的影响.方法:脑卒中后下肢运动障碍患者42例,随机分为iTBS组21例与对照组21例.2组均予常规康复训练与物理治疗,iTBS组增加对小脑蚓部的iTBS治疗,治疗2周.2组分别在治疗前后进行下肢Fulg-Meyer量表(Fugl-Meyer assessment of Lower erxtremity,FMA-LE)、6 min步行测试、60°/s向心伸膝肌力测定、Berg平衡量表(Berg balance scale,BBS)、改良Ashworth量表(modified Ashworth scale,MAS)、Barthel指数(Barthel index,BI)的评定.结果:治疗前2组患者的FMA-LE、6 min步行测试、60°/s向心伸膝肌力测定、BBS、MAS、BI评分差异均无统计学意义(P>0.05).治疗后2组患者的FMA-LE、6 min步行测试、60°/s向心伸膝肌力测定、BBS、MAS、BI评分均提高(P<0.05),iTBS组的FMA-LE、60°/s向心伸膝肌力测定、BBS、BI评分优于对照组(P<0.05).结论:iTBS刺激小脑蚓部治疗能改善脑卒中患者下肢运动功能障碍,提高日常生活活动能力.
Effects of Intermittent Theta Short Burst Pulse Stimulation to the Cerebellum Vermis on Lower Limb Motor Dysfunction in Stroke Patients
Objective:To investigate the effects of intermittent theta short burst pulse stimulation(iTBS)to the cerebellum vermis on lower limb motor dysfunction in stroke patients.Methods:A total of 42 stroke patients with post-stroke lower limb motor dysfunction were randomly divided into an iTBS group(21 cases)and a control group(21 cases).Both groups underwent standard rehabilitation training and physical therapy,with the iTBS group also receiving targeted iTBS to the cerebellar vermis for two weeks.The Fugl-Meyer assessment of Lower erxtremity(FMA-LE),6-minute walking test,60°/s concentric knee extension strength measurement,Berg Balance Scale(BBS),Modified Ashworth Scale(MAS)and Barthel Index(BI)were assessed before and after treatment in both groups.Results:There were no statistically significant differences in the FMA-LE,6-minute walking test,60°/s concentric knee extension strength measurement,BBS,MAS or BI scores between the two groups before treatment(P>0.05).After treatment,both groups showed significant improvements in the scores for the FMA-LE,6-minute walking test,60°/s concentric knee extension strength measurement,BBS,MAS and BI(P<0.05),whereas the iTBS group exhibited superior improvements in the FMA-LE,60°/s concentric knee extension strength measurement,BBS and BI scores compared to the control group(P<0.05).Conclusion:iTBS targeting the cerebellar vermis can improve lower limb motor function and daily living abilities in stroke patients.

strokemotor dysfunctionability of daily activitiesintermittent theta short burst pulse stimulation

彭瑾、谢珊、查益、袁绘、呼延梅华、张萍

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海军军医大学第一附属医院脑血管病中心 上海 200433

海军军医大学海军特色医学中心高压氧神经内科 上海 200433

脑卒中 运动障碍 生活活动能力 间歇性θ短阵脉冲刺激

2025

神经损伤与功能重建
华中科技大学同济医学院

神经损伤与功能重建

影响因子:0.977
ISSN:1001-117X
年,卷(期):2025.20(1)