Analysis of risk factors of lung abscess patients with high virulence Klebsiella pneumoniae infection
This study aims to investigate the risk factors and clinical characteristics of lung abscess patients with high virulence Klebsiella pneumoniae infection to provide more reference for early identification of high virulence infection high-risk groups.35 lung abscess patients with Klebsiella pneumoniae infection were retrospectively chosen in the period from January 2019 to January 2022 and the independent risk factors of highly virulent Klebsiella pneumoniae infection in lung abscess were evaluated by univariate and multivariate method.Combined with diabetes were independent risk factors of highly virulent Klebsiella pneumoniae infection in lung abscess(P<0.05).The drug resistance rates of cefuroxime,ceftriaxone,ceftazidime,cefepime,amoxicillin/clavulanate,piperacillin/tazobactam,cefoperazone/sulbactam and levofloxacin in high virulence group were significantly lower than classic group(P<0.05).The proportions of virulence genotype aero and rmpA+aero in the high virulence group were significantly higher than the classic group(P<0.05).High virulence Klebsiella pneumoniae infection in lung abscess was closely related to diabetes mellitus.Meanwhile,the main virulence genotype of this infection was aero.
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