Construction and evaluation of management system for curbing antibiotic resistance based on precise infection control
This study proposed a set of referable and replicable standardized management system of sensory control technology,so as to provide reference for promoting the rational application of antibiotics in hospitals and curbing bacterial drug resistance.With the establishment of a microbiological monitoring management system and rational application management system of antibiotics as the starting point and the cultivation of professional talents as the carrier,the management strategy based on the linkage of hospital-acquired infection control,medical,clinical,pharmaceutical,laboratory and nursing departments was formed and continuously optimized.To assess the effectiveness of this strategy,we conducted a retrospective analysis of data on multidrug-resistant bacteria,nosocomial infection rates,and indicators related to the rational use of antibiotics in a grade Ⅲ level A hospital in Shanghai from January 2017 to December 2022.During the development and gradual enhancement of the multi-departmental linkage management strategy,we observed an increase in the specimen submission rate of patients not treated with antibiotics from 61.55%to 64.17%during 2020 to 2022 compared to the period from 2017 to 2019.Additionally,there was a significant reduction in the infection rates of multidrug-resistant bacteria.The intensity of antibiotic use during hospitalization also decreased from 43.32(in 2018)to 40.39(in 2022).The multi-departmental linkage management system for precision infection control proposed in this study effectively promotes the rational use of antibiotics and helps mitigate bacterial drug resistance.This system can provide a reference for the work of hospital infection control departments and can be promoted and applied within medical institutions.
Precise infection controlBacteria resistanceManagement system
万方数据
