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乳腺癌免疫治疗研究进展

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世界卫生组织国际癌症研究机构发布的2020年全球最新癌症负担数据显示,乳腺癌已经成为全世界范围内发病率最高的恶性肿瘤,在现有的化疗、靶向治疗及内分泌治疗等内科治疗手段的基础上,免疫治疗的发展为乳腺癌治疗提供了全新思路.目前,免疫治疗在不同分子分型、不同阶段乳腺癌中的临床研究均取得了一定的成果.此外,对免疫治疗与其他疗法联合应用、疗效预测标志物以及免疫相关不良反应的探索也在不断进行.乳腺癌免疫治疗领域未来的研究和发展仍存在很大的空间,这些研究进展将有助于推动免疫治疗在乳腺癌中的进一步应用.
Advances in immunotherapy for breast cancer
According to the latest global cancer burden data for 2020 released by the WHO's International Agency for Research on Cancer,breast cancer has become the malignant tumor with the highest incidence worldwide.Based on existing internal medicine treatment means like chemotherapy,targeted therapy and endocrine therapy,the development of immunotherapy provides novel solutions for the treatment of breast cancer.To date,the clinical research of immunotherapy in various molecular types and stages of breast cancer has reached certain achievements.In addition,the exploration of joint application with other therapies,predictive markers for efficacy,and immune-related adverse effects is also ongoing.The research and development in the field of breast cancer immunotherapy holds a promising prospect,and approaching research advances will promote the further application of immunotherapy in breast cancer.

Breast neoplasmsImmunotherapyImmune checkpoint inhibitorsNeoadjuvant therapy

萨蔷、徐航程、王佳玉

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国家癌症中心/国家肿瘤临床医学研究中心/中国医学科学院北京协和医学院肿瘤医院内科,北京 100021

乳腺肿瘤 免疫疗法 免疫检查点抑制剂 新辅助治疗

2024

国际肿瘤学杂志
中华医学会,山东省医学科学院

国际肿瘤学杂志

CSTPCD
影响因子:0.317
ISSN:1673-422X
年,卷(期):2024.51(4)