Clinical and mechanistic research progress of TCM on ulcerative colitis of liver depression and spleen deficiency
范飒 1段晓宇 1祝康杰 1左振魁 2常久
扫码查看
点击上方二维码区域，可以放大扫码查看
作者信息
1. 河南中医药大学2020级硕士研究生，郑州 450046
2. 河南省中医院 河南中医药大学第二附属医院肛肠科，郑州 450002
折叠
摘要
肝郁脾虚证为溃疡性结肠炎（UC）的常见证型，中医基于“肝脾同治”理论治疗肝郁脾虚型UC疗效满意，不良反应较少。临床多运用以辨证论治、分期论治为主的中医内治法，以及以中药灌肠、针灸、穴位贴敷为主的中医外治法，可缓解症状、改善相关临床指标、提高患者生活质量。作用机制研究发现，具有疏肝运脾作用的中药复方主要通过调控信号通路传导、调节肠道菌群、改善炎症因子水平等多方面发挥治疗作用。 Liver depression and spleen deficiency syndrome is a common syndrome type of ulcerative colitis (UC). Based on the theory of 'collaborative treatment of liver and spleen', TCM shows its effect and less adverse reactions in the treatment of UC with liver depression and spleen deficiency. The internal treatment of TCM based on syndrome differentiation and treatment by stages, as well as the external treatment of TCM based on TCM enema therapy, acupuncture therapy and acupoint application therapy, can relieve symptoms, improve relevant clinical indicators and improve the quality of life of patients. The mechanism studies show that the TCM with the effect of soothing the liver and activating the spleen plays a therapeutic role by regulating signal pathway conduction, regulating intestinal flora, and improving the level of inflammatory factors.
Abstract
Liver depression and spleen deficiency syndrome is a common syndrome type of ulcerative colitis (UC). Based on the theory of 'collaborative treatment of liver and spleen', TCM shows its effect and less adverse reactions in the treatment of UC with liver depression and spleen deficiency. The internal treatment of TCM based on syndrome differentiation and treatment by stages, as well as the external treatment of TCM based on TCM enema therapy, acupuncture therapy and acupoint application therapy, can relieve symptoms, improve relevant clinical indicators and improve the quality of life of patients. The mechanism studies show that the TCM with the effect of soothing the liver and activating the spleen plays a therapeutic role by regulating signal pathway conduction, regulating intestinal flora, and improving the level of inflammatory factors.
关键词
结肠炎,溃疡性/肝郁脾虚/中医药疗法/综述
Key words
Colitis, ulcerative/Syndrome of stagnation of liver qi and spleen deficiency/Traditional Chinese Medicine therapy/Review
万方数据