首页|通腑法调节肠道菌群及修复肠黏膜屏障研究进展

通腑法调节肠道菌群及修复肠黏膜屏障研究进展

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肠道菌群及肠屏障功能对于肠道功能及人体健康具有重要意义.肠道菌群紊乱、肠屏障结构被破坏,会导致体内细菌移位、内毒素入血、促炎性细胞因子产生,从而引发机体各种组织损伤.中医通腑法可通过调节肠道通透性及其免疫应答、恢复肠道正常运动、调节肠道菌群结构及其代谢产物等方面影响肠道内环境,从而维护肠稳态及机体健康.对通腑法调节肠道菌群、改善肠屏障功能开展相关研究,可为进一步研究中医药与肠道微生态的关系提供参考,并为临床治疗提供思路.
Research progress in regulating intestinal flora structure and repairing intestinal mucosal barrier damage through Tongfu method
The intestinal flora and gut barrier function are of great significance for gut function and human health.When the intestinal flora is disrupted and the gut barrier structure is disrupted,it can lead to bacterial translocation,endotoxin influx into the bloodstream,and the production of pro-inflammatory factors,leading to various tissue damage in the body.Tongfu method in TCM can affect the intestinal environment by regulating intestinal permeability and immune response,restoring normal intestinal movement,and regulating the structure and metabolites of intestinal flora,thereby maintaining intestinal homeostasis and body health.The research on regulating intestinal flora and improving intestinal barrier function by Tongfu method can provide reference for further research on the relationship between TCM and intestinal microecology,and provide ideas for clinical treatment.

Therapeutic methods(TCMP)Tongfu methodIntestinal floraIntestinal mucosal barrierIntestinal barrier functionReview

吴熠姮、徐志伟、朱惠萍、俞嵩、张川、丁姮月、孙宏文

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南京中医药大学,南京 210023

南京中医药大学附属苏州市中医医院脾胃病科,苏州 215009

中医药治法 通腑法 肠道菌群 肠黏膜屏障 肠屏障功能 综述

国家中医药管理局全国中医学术流派传承工作室第二轮建设项目江苏省科技项目苏州市"科教兴卫"青年科技项目苏州市卫生计生委科技项目苏州市科技计划项目苏州市科技计划项目苏州市科技计划项目

国中医药人教函[2019]62号BK20201179KJXW2021045LCZX201817SYS201777SKY2022015SS202082

2024

10.3760/cma.j.cn115398-20230425-00349

国际中医中药杂志
中华医学会,中国中医科学院中医药信息研究所

国际中医中药杂志

CSTPCD
影响因子：0.411
ISSN：1673-4246
年,卷(期)：2024.46(4)
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