摘要
大承气汤是临床治疗阳明腑实证的经典方剂,具有通腑泄热、软坚散结功效,临床常用于治疗各种疾病引起的胃肠功能障碍.综述近年大承气汤化学成分、药理作用研究文献,并结合中药质量标志物"五原则"对大承气汤的质量标志物进行预测分析,认为大承气汤中大黄素、大黄酸、大黄酚、芦荟大黄素、辛弗林、橙皮苷、柚皮苷、厚朴酚、和厚朴酚可作为本方的质量标志物.
Abstract
Dachengqi Decoction is a classic prescription attacked by Yangming excessive syndromes in clinic,which has the effects of relieving heat,softening and dispersing knots,etc.,and is often used in the treatment of gastrointestinal dysfunction caused by various diseases.This article reviewed the recent studies on the chemical compositions and pharmacological effects of Dachengqi Decoction in recent years.On this basis,combined with the"five principles"of TCM quality markers,the quality markers of Dachengqi Decoction were predicted and analyzed.It is suggested that emodin,Rhein,chrysophanol,aloe-emodin,synephrine,hesperidin,naringin,magnolol and magnolol can be used as quality markers of Dachengqi Decoction.
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