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痛泻要方治疗消化系统疾病机制及临床应用研究进展

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近年痛泻要方化学成分研究主要针对其水煎液复方成分及挥发性成分,该方具有抗炎、抗氧化、抗肿瘤、改善肠道菌群、调控脑肠轴异常、修复肠黏膜屏障、调节机体免疫功能等作用,痛泻要方可用于肠易激综合征、溃疡性结肠炎、小儿腹泻、胆囊切除术后综合征、肿瘤术后及化疗后不良反应等的治疗.临床多以本方及其加减方内服或外用,或与其他中西医治疗手段联合应用,常获佳效.
Research progress in mechanism efficacy and clinical application of Tongxieyao Prescription in the treatment of digestive system diseases
In recent years,the research on the chemical components of Tongxieyao Prescription mainly focuses on the compound components and volatile components of its decoction.It has the effects of anti-inflammatory,antioxidant,anti-tumor,improving intestinal flora,regulating cerebral and intestinal axis abnormalities,repairing intestinal mucosal barrier,regulating body immunity,etc.It can be used for the treatment of irritable bowel syndrome,ulcerative colitis,diarrhea in children,post-cholecystectomy syndrome,postoperative tumor and discomfort caused by chemotherapy,etc.In clinical practice,Tongxieyao Prescription is often used for internal or external use,or combined with other traditional Chinese and Western medicine treatment methods,often with good efficacy.

Tong Xie Yao FangChemical componentsClinical applicationEfficacy mechanismDigestive system diseaseReview

王小嘉、张玉峰、李辽飞

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河南中医药大学第二临床医学院,郑州 450000

河南省中医院肝胆脾胃病科,郑州 450000

痛泻要方 化学成分 临床应用 疗效机制 消化系统疾病 综述

河南省科技攻关计划河南省高等学校重点科研项目

19210231042819A360016

2024

国际中医中药杂志
中华医学会,中国中医科学院中医药信息研究所

国际中医中药杂志

CSTPCD
影响因子:0.411
ISSN:1673-4246
年,卷(期):2024.46(5)
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